Results

Hepatitis Studies at the Willowbrook State School for Children with Mental Retardation
James M. DuBois
From 1956 through 1971, residents at the Willowbrook State School for Children with Mental Retardation were infected with live hepatitis in order to develop a vaccine. Parents gave permission for their children to participate in this study, often because it guaranteed acceptance into the overcrowded facility.

How Much is Enough?
Patricia Keith-Spiegel and Gerald P. Koocher
A researcher and study participants differ in opinion over what is a sufficient amount to pay prisoners for research participation.

Getting Consent to do Research with Institutionalized Children
Emily E. Anderson
Investigators studying the neurological correlates of AIDS in infected children evaluate the risks and benefits to institutionalized child participants.

Placebo Trials with Prevalent but Unproven Treatments
Emily E. Anderson
At a residential treatment center for persons with mental retardation, lithium is frequently used to treat aggressive and self-injurious adolescents. However, this use of the drug has never been systematically tested on this population. Investigators propose a placebo-control experimental design but some staff members believe this is depriving patients of an established treatment.